To develop a superior biologic drug, it is important to synthesize a benchmark reference antibody. The reference antibody can greatly facilitate the downstream development. It can help identify critical cell lines, reagents, performance characteristics, etc.
DIMA Biotechnology LTD utilizes HEK293 mammalian cell secretion expression system and we implemented a strict quality control process, including purity testing, target binding verification, etc.
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Figure 2. HEK293 cell line transfected with irrelevant protein (B) and human PD1(A) were surface stained with anti-PD1 neutralizing antibody 1μg/ml (pembrolizumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.