Clone ID | 2E12 |
---|---|
Target | |
Synonyms | EGFR;RBB;RBB1;ER1;IG61;ENA |
Host Species | Rabbit |
Description | Anti-EGFRVIII antibody(2E12); IgG1 Chimeric mAb |
Delivery | In Stock |
Uniprot ID | P00533 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1/100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. |
Usage | Research use only |
Conjugate | Unconjugated |
Anti-EGFRVIII antibody(2E12); IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-EGFRVIII (2E12) mAb on Expi293 cells transfected with human EGFRVIII (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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