Name: Human DRD2 full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP100230

Tag	C-Flag Tag
Target	DRD2
Synonyms	D2DR; D2R
Description	Human DRD2 full length protein-synthetic nanodisc
Delivery	In Stock
Uniprot ID	P14416
Expression Host	HEK293
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Gap junction, Neuroactive ligand-receptor interaction
Molecular Weight	The human full length DRD2 protein has a MW of 50.6 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing.
Usage	Research use only
Conjugate	Unconjugated

Human DRD2 full length protein-synthetic nanodisc