Clone ID | 6G7 |
---|---|
Target | |
Synonyms | C7orf15;CD112R |
Host Species | Rabbit |
Description | Anti-PVRIG antibody(6G7), IgG1 Chimeric mAb |
Delivery | In Stock |
Uniprot ID | Q6DKI7 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | ELISA, Flow Cyt |
Recommended Dilutions | ELISA 1/5000-10000;Flow Cyt 1/100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.[UniProtKB/Swiss-Prot Function] |
Usage | Research use only |
Conjugate | Unconjugated |
Anti-PVRIG antibody(6G7), IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human PVRIG protein, hFc tagged protein ( PME100090) can bind Rabbit anti-PVRIG monoclonal antibody(clone: 6G7) in a linear range of 1-100 ng/ml.
Figure 2. Flow cytometry analysis with 1μg/mL Anti-PVRIG (6G7) mAb on Expi293 cells transfected with human PVRIG (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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