| Target | |
|---|---|
| Synonyms | CAXII; CA-XII; T18816; HsT18816 |
| Description | Recombinant human CA12 Protein with C-terminal 10×His tag |
| Delivery | In Stock |
| Uniprot ID | O43570 |
| Expression Host | HEK293 |
| Tag | C-10×His tag |
| Molecular Characterization | CA12(Ala25-Ser301) 10×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 32.5 kDa after removal of the signal peptide. The apparent molecular mass of CA12-His is approximately 25-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Three transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jun 2014] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human CA12 Protein, His Tag
Price:10μg $71.00 ; 50μg $259.00 ; 100μg $389.00
Product Data
Images
Figure 1. Human CA12 Protein, His Tag on SDS-PAGE under reducing condition.
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