Clone ID | 23D8 |
---|---|
Target | |
Synonyms | PD-L1;CD274;B7-H1;PDCD1L1;PDCD1LG1 |
Host Species | Rabbit |
Description | Anti-PDL1 antibody(23D8), IgG1 Chimeric mAb |
Delivery | In Stock |
Uniprot ID | Q9NZQ7 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | WB |
Recommended Dilutions | WB 1:1000 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma. Alternative splicing results in multiple transcript variants. |
Usage | Research use only |
Anti-PDL1 antibody(23D8), IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1.Anti-PDL1 antibody (SKU# DMC100875) at 1/1000 dilution
Lane : K562-PDL1, whole cell lysate
Secondary : Goat Anti-Rabbit IgG H&L (HRP) at 1/5000 dilution
Predicted band size: 33 kDa
Observed band size: 40-60 kDa
Related products
DimAb monoclonal antibodies
SKU: DME100123 Target: PDL1
Application: ELISA; Flow Cyt
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
DimAb monoclonal antibodies
SKU: DMC100875B Target: PDL1
Application: WB
Price: 10μg $139.00 ; 100 μg $670.00 ; 500 μg $1999.00
ECD Proteins
SKU: PME-D100009 Target: PDL1
Price: 10μg $118.00; 50μg $429.00 ; 100 μg $645.00
Biosimilar reference antibodies
SKU: BME100153 Target: PDL1
Application: Flow Cyt
Price: 50μg $82.00 ; 100 μg $162.00
DimAb monoclonal antibodies
SKU: DME100123B Target: PDL1
Application: ELISA; Flow Cyt
Price: 10μg $139.00 ; 100 μg $670.00 ; 500 μg $1999.00