| Clone ID | 17A11 |
|---|---|
| Target | |
| Synonyms | TACSTD2;GA733-1;M1S1;TROP2 |
| Host Species | Rabbit |
| Description | Anti-TROP2 antibody(17A11), Rabbit mAb |
| Delivery | In Stock |
| Uniprot ID | P09758 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | WB |
| Recommended Dilutions | WB 1:1000 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-TROP2 antibody(17A11), Rabbit mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1.Anti-Trop2 antibody (SKU# DME101001) at 1/1000 dilution
Lane : A431, whole cell lysate
Secondary : Goat Anti-Rabbit IgG H&L (HRP) at 1/5000 dilution
Predicted band size: 36 kDa
Observed band size: 40 kDa
Figure 2. Flow cytometry analysis of antigen binding of rabbit anti-human TROP2 mAb(DME101001).
(A) DME101001 does not bind to CHO-S cells that do not express TROP2.
(B) A clear peak shift of DME101001 was seen compared to the control when incubated with TROP2-expressing A431 cells, indicating strong binding of DME101001 to TROP2. Antibodies were incubated at 5 μg/mL.
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