| Clone ID | 1F2 |
|---|---|
| Target | |
| Synonyms | AXL;UFO |
| Host Species | Rabbit |
| Description | Anti-AXL antibody(1F2), IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | P30530 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | WB |
| Recommended Dilutions | WB 1/1000 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-AXL antibody(1F2), IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1.Anti-AXL antibody (SKU# DMC100868) at 1/1000 dilution
Lane : Hela, whole cell lysate
Secondary : Goat Anti-Rabbit IgG H&L (HRP) at 1/5000 dilution
Predicted band size: 98 kDa
Observed band size: 128 kDa
Figure 2. Flow cytometry analysis of antigen binding of anti-human AXL mAb(DMC100868).
(A) DMC100868 does not bind to CHO-S cells that do not express AXL.
(B) A clear peak shift of DMC100868 was seen compared to the control when incubated with AXL-expressing Hela cells, indicating strong binding of DMC100868 to AXL. Antibodies were incubated at 5 μg/mL.
Related Products
Biosimilar reference antibodies
SKU: BME100175P Target: AXL
Application: Flow Cyt
Price: 100 test $192.00
Biosimilar reference antibodies
SKU: BME100569P Target: AXL
Application: N/A
Price: 100 test $192.00
Monoclonal antibodies
SKU: DMC100868P Target: AXL
Application: Flow Cyt
Price: 100 test $550.00
Biosimilar reference antibodies
SKU: BME100699B Target: AXL
Application: N/A
Price: 50μg $99.00 ; 100 μg $199.00
Monoclonal antibodies
SKU: DMC100868B Target: AXL
Application: WB
Price: 10μg $139.00 ; 100 μg $670.00 ; 500 μg $1999.00