Biotinylated Anti-Dxd antibody(1E6); Rabbit mAb

Price: 10μg $139.00 ; 100 μg $670.00 ; 500 μg $1999.00

SKU: DME101027B Category: Monoclonal antibodies

Clone ID	1E6
Target	Dxd
Synonyms	N.A.
Host Species	Rabbit
Description	Biotinylated Anti-Dxd antibody(1E6); Rabbit mAb
Delivery	2-3 weeks
Uniprot ID	N.A.
IgG type	Rabbit IgG
Clonality	Monoclonal
Reactivity	N.A.
Applications	ELISA
Recommended Dilutions	ELISA 1:5000-10000
Purification	Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	Dxd is a potent anti-cancer drug, acting as an alkaloid camptothecin analog and a DNA topoisomerase I inhibitor. It forms a stable complex with topoisomerase I and DNA, impeding DNA replication and inducing cancer cell death. Dxd is utilized as a payload in specific antibody-drug conjugates (ADCs), with examples such as trastuzumab deruxtecan targeting HER2 and patritumab deruxtecan targeting HER3.
Usage	Research use only
Conjugate	Biotinylated