| Target | |
|---|---|
| Synonyms | FIL1; FIL1E; IL1F6; IL-1F6; IL1(EPSILON); FIL1(EPSILON) |
| Description | Recombinant human IL36A Protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q9UHA7 |
| Expression Host | HEK293 |
| Tag | C-Human Fc tag |
| Molecular Characterization | IL36A(Lys6-Phe158) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 43.2 kDa after removal of the signal peptide. The apparent molecular mass of IL36A-hFc is approximately 35-70 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a cytokine that can activate NF-kappa-B and MAPK signaling pathways to generate an inflammatory response. The encoded protein functions primarily in skin and demonstrates increased expression in psoriasis. In addition, decreased expression of this gene has been linked to a poor prognosis in both hepatocellular carcinoma and colorectal cancer patients. [provided by RefSeq, Nov 2015] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human IL36A Protein, hFc Tag
Price: 10μg $95.00 ; 50μg $330.00 ; 100μg $500.00
Product Data
Images
Figure 1. Human IL36A Protein, hFc Tag on SDS-PAGE under reducing condition.
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