| Target | |
|---|---|
| Description | Monoclonal Cell Line Derived from CHO-S Cells, Engineered for Stable Expression of Human TNFRSF10B Using Lentiviral Technology |
| Host Cells | CHO-S |
| Uniprot ID | O14763 |
| Applications | FACS Data |
| Growth media | DMEM+10% FBS+1% P.S+Gln+2 ug/mL Puromycin |
| Package | 5E6 Cells/mL |
| Host Species | Human |
| Suggested Control | SKU: BME100032 |
| Warranty and Disclaimer | 1. Please inspect cells upon receipt and report any issues promptly. 2. We offer one-time replacements for issues reported within a week of receipt. 3. User-induced issues are not eligible for free replacements. 4. We do not accept liability for damages resulting from cell use, storage, or loss. 5. Feedback received more than one month after receipt will not be processed. |
| Storage & Shipping | Cells are shipped using dry ice and require liquid nitrogen storage for long term preservation. |
| Synonyms | TNFRSF10B;TRAILR2;TRAIL-R2;CD262;DR5;KILLER;TRICK2;ZTNFR9;TRICKB |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily; and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10:TRAIL:APO-2L); and transduces an apoptosis signal. Studies with FADD-deficient mice suggested that FADD; a death domain containing adaptor protein; is required for the apoptosis mediated by this protein. Two transcript variants encoding different isoforms and one non-coding transcript have been found for this gene. |
| Usage | For research use only. |
Hu_TNFRSF10B CHO-S Cell Line
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Figure 1. Flow cytometry analysis of human TNFRSF10B overexpression using Hu_TNFRSF10B CHO-S Cell Line (Cat. No. CEL100064) and Anti-TNFRSF10B (tigatuzumab biosimilar) mAb (Cat. No. BME100032)