Target | |
---|---|
Synonyms | GluD2, SCAR18 |
Description | Human GRID2 full length protein-synthetic nanodisc |
Delivery | 6~8weeks |
Uniprot ID | O43424 |
Expression Host | HEK293 |
Protein Families | Ion Channels: Glutamate Receptors |
Protein Pathways | N/A |
Molecular Weight | The human full length GRID2 protein has a MW of 113.4kDa |
Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with pH lower than 6.5 in subsequent experiments. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans. [provided by RefSeq, Apr 2014] |
Usage | Research use only |
![Awaiting product image](https://www.dimabio.com/wp-content/uploads/woocommerce-placeholder-400x400.png)
Human GRID2 full length protein-synthetic nanodisc
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Related products
Full Length Transmembrane Proteins
SKU: FLP100010 Target: GPRC5D
Price: 50 μg $1200.00 ; 100 μg $1600.00
Full Length Transmembrane Proteins
SKU: FLP100009 Target: CB1
Price: 50 μg $1200.00 ; 100 μg $1600.00
Full Length Transmembrane Proteins
SKU: FLP100013 Target: SSTR2
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Full Length Transmembrane Proteins
SKU: FLP100001 Target: CCR8
Price: 50 μg $1200.00 ; 100 μg $1600.00
Full Length Transmembrane Proteins
SKU: FLP100004 Target: CLDN6
Price: 50 μg $1200.00 ; 100 μg $1600.00
Full Length Transmembrane Proteins
SKU: FLP100019 Target: ADORA2A
Price: 50 μg $1200.00 ; 100 μg $1600.00
Full Length Transmembrane Proteins
SKU: FLP100026 Target: CD20
Price: 50 μg $1200.00 ; 100 μg $1600.00
Full Length Transmembrane Proteins
SKU: FLP100032 Target: SLC25A4
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Full Length Transmembrane Proteins
SKU: FLP100011 Target: GPRC5D
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00