| Tag | C-Flag&Strep Tag |
|---|---|
| Target | |
| Synonyms | FSGS2, TRP6 |
| Description | Human TRPC6-Strep full length protein-synthetic nanodisc |
| Delivery | 6~8weeks |
| Uniprot ID | Q9Y210 |
| Expression Host | HEK293 |
| Protein Families | Ion Channels: Transient receptor potential |
| Protein Pathways | N/A |
| Molecular Weight | The human full length TRPC6-Strep protein has a MW of 106.3 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human TRPC6-Strep full length protein-synthetic nanodisc
Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00
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