Name: Human GLRA1-Strep full length protein-synthetic nanodisc - DIMA Biotechnology
SKU: FLP120819

Tag	C-Flag&Strep Tag
Target	GLRA1
Synonyms	HKPX1, STHE
Description	Human GLRA1-Strep full length protein-synthetic nanodisc
Delivery	6~8weeks
Uniprot ID	P23415
Expression Host	HEK293
Protein Families	Ion Channels: Cys-loop Receptors
Protein Pathways	N/A
Molecular Weight	The human full length GLRA1-Strep protein has a MW of 52.6 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor, which mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Multiple transcript variants encoding different isoforms have been found. [provided by RefSeq, Dec 2015]
Usage	Research use only
Conjugate	Unconjugated

Human GLRA1-Strep full length protein-synthetic nanodisc