Clone ID | DM50 |
---|---|
Target | |
Synonyms | CTLA4; CD152 |
Host Species | Rabbit |
Description | PE-conjugated Anti-CTLA-4 antibody(DM50); Rabbit mAb |
Delivery | 3-4 weeks |
Uniprot ID | P16410 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain; a transmembrane domain; and a cytoplasmic tail. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond; while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus; Graves disease; Hashimoto thyroiditis; celiac disease; systemic lupus erythematosus; thyroid-associated orbitopathy; and other autoimmune diseases. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-CTLA-4 antibody(DM50); Rabbit mAb
Price: 100 test $550.00
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