| Clone ID | DM50 |
|---|---|
| Target | |
| Synonyms | CTLA4; CD152 |
| Host Species | Rabbit |
| Description | PE-conjugated Anti-CTLA-4 antibody(DM50); Rabbit mAb |
| Delivery | 3-4 weeks |
| Uniprot ID | P16410 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Liquid，PBS with 0.05% Proclin300, 1% BSA |
| Storage & Shipping | Store at 2°C-8°C for 6 months |
| Background | This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain; a transmembrane domain; and a cytoplasmic tail. Alternate transcriptional splice variants; encoding different isoforms; have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond; while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus; Graves disease; Hashimoto thyroiditis; celiac disease; systemic lupus erythematosus; thyroid-associated orbitopathy; and other autoimmune diseases. |
| Usage | Research use only |
| Conjugate | PE-conjugated |
PE-conjugated Anti-CTLA-4 antibody(DM50); Rabbit mAb
Price: 100 test $550.00
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