Clone ID | DM78 |
---|---|
Target | |
Synonyms | AITR; GITR; TNFRSF18; CD357 |
Host Species | Rabbit |
Description | PE-conjugated Anti-GITR antibody(DM78); Rabbit mAb |
Delivery | 3-4 weeks |
Uniprot ID | Q9Y5U5 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation; and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25( )CD4( ) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-GITR antibody(DM78); Rabbit mAb
Price: 100 test $550.00
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