PE-conjugated Anti-GITR antibody(DM80); Rabbit mAb

Price: 100 test $550.00

SKU: DME100080P Category: Monoclonal antibodies

Clone ID	DM80
Target	GITR
Synonyms	AITR; GITR; TNFRSF18; CD357
Host Species	Rabbit
Description	PE-conjugated Anti-GITR antibody(DM80); Rabbit mAb
Delivery	3-4 weeks
Uniprot ID	Q9Y5U5
IgG type	Rabbit IgG
Clonality	Monoclonal
Reactivity	Human
Applications	Flow Cyt
Recommended Dilutions	Flow Cyt 1:100
Purification	Purified from cell culture supernatant by affinity chromatography
Formulation & Reconstitution	Liquid，PBS with 0.05% Proclin300, 1% BSA
Storage & Shipping	Store at 2°C-8°C for 6 months
Background	This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation; and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25( )CD4( ) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Usage	Research use only
Conjugate	PE-conjugated