Clone ID | DM193 |
---|---|
Target | |
Synonyms | B220; CD45; CD45R; GP180; L-CA; LCA; LY5; T200 |
Host Species | Rabbit |
Description | PE-conjugated Anti-CD45 antibody(DM193); Rabbit mAb |
Delivery | 3-4 weeks |
Uniprot ID | P08575 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitosis; and oncogenic transformation. This PTP contains an extracellular domain; a single transmembrane segment and two tandem intracytoplasmic catalytic domains; and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes; or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases; and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene; which encode distinct isoforms; have been reported. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-CD45 antibody(DM193); Rabbit mAb
Price: 100 test $550.00
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