Clone ID | DMC438 |
---|---|
Target | |
Synonyms | EDSS1; LNIR; nectin-4; PRR4; PVRL4 |
Host Species | Rabbit |
Description | PE-conjugated Anti-Nectin4 antibody(DMC438); IgG1 Chimeric mAb |
Delivery | 3-4 weeks |
Uniprot ID | Q96NY8 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17:TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1; an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined. |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-Nectin4 antibody(DMC438); IgG1 Chimeric mAb
Price: 100 test $550.00
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