Clone ID | DMC460 |
---|---|
Target | |
Synonyms | CD334; JTK2; TKF |
Host Species | Rabbit |
Description | PE-conjugated Anti-FGFR4 antibody(DMC460), IgG1 Chimeric mAb |
Delivery | 3-4 weeks |
Uniprot ID | P22455 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Liquid,PBS with 0.05% Proclin300, 1% BSA |
Storage & Shipping | Store at 2°C-8°C for 6 months |
Background | The protein encoded by this gene is a tyrosine kinase and cell surface receptor for fibroblast growth factors. The encoded protein is involved in the regulation of several pathways; including cell proliferation; cell differentiation; cell migration; lipid metabolism; bile acid biosynthesis; vitamin D metabolism; glucose uptake; and phosphate homeostasis. This protein consists of an extracellular region; composed of three immunoglobulin-like domains; a single hydrophobic membrane-spanning segment; and a cytoplasmic tyrosine kinase domain. The extracellular portion interacts with fibroblast growth factors; setting in motion a cascade of downstream signals; ultimately influencing mitogenesis and differentiation. [provided by RefSeq; Aug 2017] |
Usage | Research use only |
Conjugate | PE-conjugated |
PE-conjugated Anti-FGFR4 antibody(DMC460), IgG1 Chimeric mAb
Price: 100 test $550.00
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