| Target | |
|---|---|
| Synonyms | CPSD; CLN10; HEL-S-130P |
| Description | Recombinant human CTSD Protein with C-terminal 10×His tag |
| Delivery | In Stock |
| Uniprot ID | P07339 |
| Expression Host | HEK293 |
| Tag | C-10×His tag |
| Molecular Characterization | CTSD(Leu21-Leu412) 10×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 44.0 kDa after removal of the signal peptide. The apparent molecular mass of CTSD-His is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human CTSD Protein, His Tag
Price:10μg $90.00 ; 50μg $320.00 ; 100μg $480.00
Product Data
Images
Figure 1. Human CTSD Protein, His Tag on SDS-PAGE under reducing condition.
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