Target | |
---|---|
Synonyms | IBP2;IGF-BP53 |
Description | Recombinant human IGFBP2 protein with C-terminal human Fc tag |
Delivery | Under development |
Uniprot ID | P18065 |
Expression Host | HEK293 |
Tag | C-Human Fc Tag |
Molecular Characterization | IGFBP2(Ala36-Gln325) hFc(Glu99-Ala330) |
Molecular Weight | The protein has a predicted molecular mass of 57.3 kDa after removal of the signal peptide. |
Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is one of six similar proteins that bind insulin-like growth factors I and II (IGF-I and IGF-II). The encoded protein can be secreted into the bloodstream, where it binds IGF-I and IGF-II with high affinity, or it can remain intracellular, interacting with many different ligands. High expression levels of this protein promote the growth of several types of tumors and may be predictive of the chances of recovery of the patient. Several transcript variants, one encoding a secreted isoform and the others encoding nonsecreted isoforms, have been found for this gene. [provided by RefSeq, Sep 2015] |
Usage | Research use only |
Conjugate | Unconjugated |
Human IGFBP2 Protein, hFc Tag
Price: 10μg $72.00; 50μg $274.00 ; 100 μg $411.00
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SKU: PME101125 Target: IGFBP2
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