| Target | |
|---|---|
| Synonyms | ADAM 15;MDC-15 |
| Description | Recombinant human ADAM15 protein with C-terminal human Fc tag |
| Delivery | In Stock |
| Uniprot ID | Q13444 |
| Expression Host | HEK293 |
| Tag | C-Human Fc Tag |
| Molecular Characterization | ADAM15(Leu18-Thr696) hFc(Glu99-Ala330) |
| Molecular Weight | The protein has a predicted molecular mass of 100.0 kDa after removal of the signal peptide. The apparent molecular mass of ADAM15-hFc is approximately 100-130 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human ADAM15 Protein, hFc Tag
Price: 10μg $120.00 ; 50μg $450.00 ; 100 μg $660.00
Product Data
Images
Figure 1. Human ADAM15 Protein, hFc Tag on SDS-PAGE under reducing condition.
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