| Target | |
|---|---|
| Synonyms | B7DC;bA574F11.2;Btdc;CD273;PD-L2;PDCD1L2;PDL2 |
| Description | Recombinant human PDL2 protein with C-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | Q9BQ51 |
| Expression Host | HEK293 |
| Tag | C-6×His Tag |
| Molecular Characterization | PDL2(Leu20-Pro219) 6×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 23.4 kDa after removal of the signal peptide.The apparent molecular mass of PDL2-His is approximately 35-55 kDa due to glycosylation. |
| Purity | The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity).[UniProtKB/Swiss-Prot Function] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human PDL2 Protein, His Tag
Price: 10μg $85.00; 50μg $330.00 ; 100 μg $500.00
Product Data
Images
Figure 1. Human PDL2 Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. Flow cytometry analysis with 15 μg/mL Human PDL2 Protein, His tag (PME100518) on Expi293 cells transfected with human PD1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human PDL2 Protein, His Tag (PME100518) can bind Anti-PDL2 antibody(DM169), Rabbit mAb in a linear range of 0.13–3.20 ng/mL.
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