| Clone ID | DMC390 |
|---|---|
| Target | |
| Synonyms | BETA-HFR; FBP; FBP:PL-1; FOLR1; FR-BETA; FR-P3; FRbeta |
| Host Species | Rabbit |
| Description | Anti-FOLR2 antibody(DMC390); IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | P14207 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a member of the folate receptor (FOLR) family; and these genes exist in a cluster on chromosome 11. Members of this gene family have a high affinity for folic acid and for several reduced folic acid derivatives; and they mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This protein has a 68% and 79% sequence homology with the FOLR1 and FOLR3 proteins; respectively. Although this protein was originally thought to be specific to placenta; it can also exist in other tissues; and it may play a role in the transport of methotrexate in synovial macrophages in rheumatoid arthritis patients. Multiple transcript variants that encode the same protein have been found for this gene. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-FOLR2 antibody(DMC390); IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-FOLR2 (DMC390) on Expi293 cells transfected with human FOLR2 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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