| Clone ID | DMC444 |
|---|---|
| Target | |
| Synonyms | CD157 |
| Host Species | Rabbit |
| Description | Anti-BST1 antibody(DMC444); IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | Q10588 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Bone marrow stromal cell antigen-1 is a stromal cell line-derived glycosylphosphatidylinositol-anchored molecule that facilitates pre-B-cell growth. The deduced amino acid sequence exhibits 33% similarity with CD38. BST1 expression is enhanced in bone marrow stromal cell lines derived from patients with rheumatoid arthritis. The polyclonal B-cell abnormalities in rheumatoid arthritis may be; at least in part; attributed to BST1 overexpression in the stromal cell population. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-BST1 antibody(DMC444); IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-BST1 (DMC444) on Expi293 cells transfected with human BST1 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of anti-human BST1 mAb(DMC100444).
(A) DMC100444 does not bind to CHO-S cells that do not express BST1.
(B) A clear peak shift of DMC100444 was seen compared to the control when incubated with BST1-expressing THP-1 cells, indicating strong binding of DMC100444 to BST1. Antibodies were incubated at 5 μg/mL.
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