| Tag | C-Flag Tag |
|---|---|
| Target | |
| Synonyms | N.A. |
| Description | Human CLPTM1 full length protein-synthetic nanodisc |
| Delivery | In Stock |
| Uniprot ID | O96005 |
| Expression Host | HEK293 |
| Protein Families | Transmembrane |
| Protein Pathways | N.A. |
| Molecular Weight | The human full length CLPTM1 protein has a MW of 76.1 kDa |
| Formulation & Reconstitution | Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. Do not use solvents with a pH below 6.5 or those containing high concentrations of divalent metal ions (greater than 5 mM) in subsequent experiments. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C(Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Involved in GABAergic but not glutamatergic transmission. Binds and traps GABAA receptors in the endoplasmic reticulum (ER). Modulates postsynaptic GABAergic transmission, and therefore inhibitory neurotransmission, by reducing the plasma membrane expression of these receptors. Altered GABAergic signaling is one among many causes of cleft palate. Might function as a lipid scramblase, translocating lipids in membranes from one leaflet to the other one. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human CLPTM1 full length protein-synthetic nanodisc
Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00
Product Data
Images
Figure1. Elisa plates were pre-coated with Flag Tag CLPTM1-Nanodisc (0.2μg/per well). Serial diluted anti-Flag monoclonal antibody solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-Flag monoclonal antibody binding with CLPTM1-Nanodisc is 5.286ng/ml.
Figure2. Human CLPTM1-Nanodisc, Flag Tag on SDS-PAGE
Related Products
Full Length Transmembrane Proteins
SKU: FLP120110 Target: CLPTM1
Price: 10 μg $810.00 ; 50 μg $3960.00 ; 100 μg $7200.00