| Common Name | CD74-DOX (ADC),hLL1,hLL1-DOX (ADC),MEDI-115 |
|---|---|
| Synonyms | DHLAG |
| Applications | ELISA, Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000, Flow Cyt 1:100 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Host Species | Humanized |
| IgG type | IgG1(K97R) |
| Reactivity | Human |
| Target | |
| Uniprot ID | P04233 |
| Description | Anti-CD74(milatuzumab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-CD74(milatuzumab biosimilar) mAb
Price: 50μg $82.00 ; 100 μg $162.00
Product Data
Images
Figure 1. Flow cytometry analysis with 15μg/mL Anti-CD74(milatuzumab biosimilar) mAb (BME100170) on Expi293 cells transfected with Human CD74 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CD74 (73-296) Protein, hFc Tag(PME100642) can bind Anti-CD74(milatuzumab biosimilar) mAb(BME100170) in a linear range of 0.64–16 ng/mL. In order to specifically detect BME100170, mouse anti-human Fab-specific antibody was used as detection antibody.
Figure 3. Flow cytometry analysis of antigen binding of anti-human CD74 mAb(BME100170).
(A) BME100170 does not bind to 293T cells that do not express CD74.
(B) A clear peak shift of BME100170 was seen compared to the control when incubated with CD74-expressing Raji cells, indicating strong binding of BME100170 to CD74. Antibodies were incubated at 5 μg/mL.
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