Common Name | enfortumab |
---|---|
Synonyms | EDSS1;LNIR;nectin-4;PRR4;PVRL4 |
Applications | ELISA; Flow Cyt |
Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Host Species | Homo sapiens |
IgG type | IgG1 |
Reactivity | Human |
Target | |
Uniprot ID | Q96NY8 |
Description | Anti-Nectin-4(enfortumab biosimilar) mAb |
Delivery | In Stock |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
Usage | Research use only |
Conjugate | Unconjugated |
Anti-Nectin-4(enfortumab biosimilar) mAb
Price: 50μg $82.00 ; 100 μg $162.00
Product Data
Images
Figure 1. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human NECTIN-4 Protein, His Tag PME100874 can bind Anti-Nectin-4 Neutralizing antibody ( BME100088) in a linear range of 0.61–39.06 ng/mL.
Figure 2. Flow cytometry analysis with 1 μg/mL Anti-Nectin-4 (enfortumab biosimilar) mAb (BME100088) on Expi293 cells transfected with Human Nectin-4 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 3. Flow cytometry analysis of antigen binding of anti-human Nectin-4 mAb(BME100088).
(A) BME100088 does not bind to 293T cells that do not express Nectin-4.
(B) A clear peak shift of BME100088 was seen compared to the control when incubated with Nectin-4-expressing A431 cells, indicating strong binding of BME100088 to Nectin-4. Antibodies were incubated at 2 μg/mL.
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