| Common Name | BYM338 |
|---|---|
| Synonyms | AVR2B; ACTR-IIB |
| Applications | ELISA, Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000, Flow Cyt 1:100 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Host Species | Homo sapiens |
| IgG type | IgG1(K97R,L117A,L118A) |
| Reactivity | Human |
| Target | |
| Uniprot ID | Q13705 |
| Description | Anti-ACVR2B(bimagrumab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized antibodies are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only |
| Conjugate | Unconjugated |
| DIMA Disclaimer | All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
Anti-ACVR2B(bimagrumab biosimilar) mAb
Price: 50 μg $82.00 ; 100 μg $162.00
Product Data
Images
Figure 1. Flow cytometry analysis with 15μg/mL Anti-ACVR2B(bimagrumab biosimilar) mAb (BME100228) on Expi293 cells transfected with Human ACVR2B protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis with 1μg/mL Anti-ACVR2B(bimagrumab biosimilar) mAb (BME100228) on Expi293 cells transfected with Human ACVR2A protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human ACVR2B Protein, hFc Tag (PME101551) can bind Anti-ACVR2B(bimagrumab biosimilar) mAb (BME100228) in a linear range of 0.64–80 ng/mL.In order to specifically detect BME100228, mouse anti-human Fab-specific antibody was used as detection antibody.
Figure 4. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human ACVR2A(20-135) Protein, His Tag (PME101716) can bind Anti-ACVR2B(bimagrumab biosimilar) mAb (BME100228) in a linear range of 0.13–16 ng/mL.
Figure 5. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human ACVR2B(19-137) Protein, His Tag (PME101717) can bind Anti-ACVR2B(bimagrumab biosimilar) mAb (BME100228) in a linear range of 0.64–80 ng/mL.
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