| Clone ID | DM158 |
|---|---|
| Target | |
| Synonyms | AXL;UFO |
| Host Species | Rabbit |
| Description | Anti-AXL antibody(DM158); Rabbit mAb |
| Delivery | In Stock |
| Uniprot ID | P30530 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal; followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth; migration; aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-AXL antibody(DM158); Rabbit mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-AXL (DM158) on Expi293 cells transfected with human AXL (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of rabbit anti-human AXL mAb(DME100158).
(A) DME100158 does not bind to 293T cells that do not express AXL.
(B) A clear peak shift of DME100158 was seen compared to the control when incubated with AXL-expressing Hela cells, indicating strong binding of DME100158 to AXL. Antibodies were incubated at 2 μg/mL.
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