Clone ID | DM172 |
---|---|
Target | |
Synonyms | CSF3R;CD114;GCSFR |
Host Species | Rabbit |
Description | Anti-CD114 antibody(DM172); Rabbit mAb |
Delivery | In Stock |
Uniprot ID | Q99062 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | ELISA; Flow Cyt |
Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene is the receptor for colony stimulating factor 3; a cytokine that controls the production; differentiation; and function of granulocytes. The encoded protein; which is a member of the family of cytokine receptors; may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome; also known as severe congenital neutropenia. |
Usage | Research use only;All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
Conjugate | Unconjugated |
Anti-CD114 antibody(DM172); Rabbit mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-CD114 (DM172) on Expi293 cells transfected with human CD114 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of rabbit anti-human CD114 mAb(DME100172).
(A) DME100172 does not bind to CHO-S cells that do not express CD114.
(B) A clear peak shift of DME100172 was seen compared to the control when incubated with CD114-expressing THP-1 cells, indicating strong binding of DME100172 to CD114. Antibodies were incubated at 5 μg/mL.
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