| Clone ID | DMC269 |
|---|---|
| Target | |
| Synonyms | CD44;CDW44;CSPG8;ECMR-III;HCELL;HUTCH-I;IN;LHR;MC56;MDU2;MDU3;MIC4;Pgp1;Epican |
| Host Species | Rabbit |
| Description | Anti-CD44 antibody(DMC269); IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | P16070 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions; cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands; such as osteopontin; collagens; and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation; recirculation and homing; hematopoiesis; and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms; however; the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein; and may be related to tumor metastasis. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-CD44 antibody(DMC269); IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-CD44 (DMC269) on Expi293 cells transfected with human CD44 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of anti-human CD44 mAb(DMC100269).
(A) DMC100269 does not bind to CHO-S cells that do not express CD44.
(B) A clear peak shift of DMC100269 was seen compared to the control when incubated with CD44-expressing THP-1 cells, indicating strong binding of DMC100269 to CD44. Antibodies were incubated at 5 μg/mL.
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