| Clone ID | 1G6 |
|---|---|
| Target | |
| Synonyms | TP120 |
| Host Species | Rabbit |
| Description | Anti-CD6 antibody(1G6); IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | P30203 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1/100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-CD6 antibody(1G6); IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-CD6 (1G6) mAb on Expi293 cells transfected with human CD6 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of anti-human CD6 mAb(DMC101005).
(A) DMC101005 does not bind to CHO-S cells that do not express CD6.
(B) A clear peak shift of DMC101005 was seen compared to the control when incubated with CD6-expressing HUT78 cells, indicating strong binding of DMC101005 to CD6. Antibodies were incubated at 5 μg/mL.
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