Common Name | SGN-70, h1F6 |
---|---|
Synonyms | CD70;CD27L;CD27LG;TNFSF7 |
Applications | ELISA; Flow Cyt |
Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Host Species | Homo sapiens |
IgG type | IgG1 |
Reactivity | Human |
Target | |
Uniprot ID | P32970 |
Description | Anti-CD70 (vorsetuzumab biosimilar) mAb |
Delivery | In Stock |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
Usage | Research use only;All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
Conjugate | Unconjugated |
Anti-CD70 (vorsetuzumab biosimilar) mAb
Price: 50μg $82.00 ; 100 μg $162.00
Product Data
Images
Figure 1 . ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human CD70, mFc-His tagged protein PME100042 can bind Anti-CD70 Neutralizing antibody in a linear range of 3.91-139.9 ng/ml.
Figure 2. HEK293 cell line transfected with irrelevant protein (B) and human CD70 (A) were surface stained with anti-CD70 neutralizing antibody 1μg/ml (vorsetuzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.
Figure 3. Flow cytometry analysis of antigen binding of anti-human CD70 mAb(BME100005).
(A) A clear peak shift of BME100005 was seen compared to the control when incubated with CD70-expressing THP1 cells, indicating strong binding of BME100005 to CD70. Antibodies were incubated at 2 μg/mL.
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