| Clone ID | 1B5 |
|---|---|
| Target | |
| Synonyms | CEACAM-5;CD66e;CEA;Meconium antigen 100 |
| Host Species | Rabbit |
| Description | Anti-CEACAM5 antibody(1B5), IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | P06731 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | WB |
| Recommended Dilutions | WB 1:1000 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a cell surface glycoprotein that represents the founding member of the carcinoembryonic antigen (CEA) family of proteins. The encoded protein is used as a clinical biomarker for gastrointestinal cancers and may promote tumor development through its role as a cell adhesion molecule. Additionally, the encoded protein may regulate differentiation, apoptosis, and cell polarity. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants. |
| Usage | Research use only |
| Conjugate | Unconjugated |
| DIMA Disclaimer | All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
Anti-CEACAM5 antibody(1B5), IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1.Anti-CEACAM5 antibody (SKU# DMC100120) at 1/1000 dilution
Lane : HT55, whole cell lysate
Secondary : Goat Anti-Rabbit IgG H&L (HRP) at 1/5000 dilution
Predicted band size: 76kDa
Observed band size: 50，250 kDa
Figure 2. Flow cytometry analysis of antigen binding of anti-human CEACAM5 mAb(DMC100120).
(A) DMC100120 does not bind to CHO-S cells that do not express CEACAM5.
(B) A clear peak shift of DMC100120 was seen compared to the control when incubated with CEACAM5-expressing MKN45 cells, indicating strong binding of DMC100120 to CEACAM5. Antibodies were incubated at 5 μg/mL.
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