| Clone ID | DMC685 |
|---|---|
| Target | |
| Synonyms | CD66c; CEAL; NCA |
| Host Species | Rabbit |
| Description | Anti-CEACAM6 antibody(DMC685); IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | P40199 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a protein that belongs to the carcinoembryonic antigen (CEA) family whose members are glycosyl phosphatidyl inositol (GPI) anchored cell surface glycoproteins. Members of this family play a role in cell adhesion and are widely used as tumor markers in serum immunoassay determinations of carcinoma. This gene affects the sensitivity of tumor cells to adenovirus infection. The protein encoded by this gene acts as a receptor for adherent-invasive E. coli adhesion to the surface of ileal epithelial cells in patients with Crohn's disease. This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19. [provided by RefSeq; Apr 2014] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-CEACAM6 antibody(DMC685); IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-CEACAM6(DMC685) on Expi293 cells transfected with human CEACAM6(Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of anti-human CEACAM6 mAb(DMC100685).
(A) DMC100685 does not bind to jurkat cells that do not express CEACAM6.
(B) A clear peak shift of DMC100685 was seen compared to the control when incubated with CEACAM6-expressing SNU-5 cells, indicating strong binding of DMC100685 to CEACAM6. Antibodies were incubated at 5 μg/ml.
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