| Clone ID | DMC679 |
|---|---|
| Target | |
| Synonyms | Blr1; CXC-R5; CXCR-5; Gpcr6; MDR15 |
| Host Species | Rabbit |
| Description | Anti-CXCR5 antibody(DMC679); IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | P32302; A0N0R2; A8K647; Q2YD84 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt; IHC |
| Recommended Dilutions | Flow Cyt 1:100; IHC 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes.[UniProtKB:Swiss-Prot Function] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-CXCR5 antibody(DMC679), IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-CXCR5(DMC679) on Expi293 cells transfected with human CXCR5(Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of anti-human CXCR5 mAb(DMC100679).
(A) DMC100679 does not bind to Hela cells that do not express CXCR5.
(B) A clear peak shift of DMC100679 was seen compared to the control when incubated with CXCR5-expressing Raji cells, indicating strong binding of DMC100679 to CXCR5. Antibodies were incubated at 5 μg/mL.
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