| Clone ID | DMC424 |
|---|---|
| Target | |
| Synonyms | Ep; EPR; ER |
| Host Species | Rabbit |
| Description | Anti-EREG antibody(DMC424); IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | O14944 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation; wound healing; oocyte maturation; and cell proliferation. Additionally; the encoded protein may promote the progression of cancers of various human tissues. |
| Usage | Research use only；All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
| Conjugate | Unconjugated |
Anti-EREG antibody(DMC424), IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-EREG (DMC424) on Expi293 cells transfected with human EREG (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of anti-human EREG mAb(DMC100424).
(A) DMC100424 does not bind to Jurkat cells that do not express EREG.
(B) A clear peak shift of DMC100424 was seen compared to the control when incubated with EREG-expressing SiHa cells, indicating strong binding of DMC100424 to EREG. Antibodies were incubated at 5 μg/mL.
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