| Clone ID | DMC424 |
|---|---|
| Target | |
| Synonyms | Ep; EPR; ER |
| Host Species | Rabbit |
| Description | Anti-EREG antibody(DMC424); IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | O14944 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a secreted peptide hormone and member of the epidermal growth factor (EGF) family of proteins. The encoded protein is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4). The encoded protein may be involved in a wide range of biological processes including inflammation; wound healing; oocyte maturation; and cell proliferation. Additionally; the encoded protein may promote the progression of cancers of various human tissues. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-EREG antibody(DMC424), IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-EREG (DMC424) on Expi293 cells transfected with human EREG (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Figure 2. Flow cytometry analysis of antigen binding of anti-human EREG mAb(DMC100424).
(A) DMC100424 does not bind to Jurkat cells that do not express EREG.
(B) A clear peak shift of DMC100424 was seen compared to the control when incubated with EREG-expressing SiHa cells, indicating strong binding of DMC100424 to EREG. Antibodies were incubated at 5 μg/mL.
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