| Common Name | MDX-1333, MEDI-546, anifrolumab-fnia |
|---|---|
| Synonyms | IFN-R-1;CRF2-1;IFNAR |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Host Species | Homo sapiens |
| IgG type | IgG1 |
| Reactivity | Human |
| Target | |
| Uniprot ID | P17181 |
| Description | Anti-IFNAR1(anifrolumab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-IFNAR1(anifrolumab biosimilar) mAb
Price: 50μg $82.00 ; 100 μg $162.00
Product Data
Images
Figure 1. ELISA plate pre-coated by 1 μg/mL (100 μL/well) Human IFNAR1 Protein, His Tag (PME100958) can bind Anti-IFNAR1 Neutralizing antibody (BME100117) in a linear range of 0.61–39.06 ng/mL.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human IFNAR1 Protein, hFc Tag (PME100773) can bind Anti-IFNAR1 Neutralizing antibody (BME100117) in a linear range of 0.73–187.50 ng/mL. In order to specifically detect BME100117, mouse anti-human Fab-specific antibody was used as detection antibody.
Figure 3. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human IFNAR1 Protein, mFc Tag (PME100737) can bind Anti-IFNAR1 Neutralizing antibody (BME100117) in a linear range of 1.22–312.50 ng/mL.
Figure 4. Flow cytometry analysis with 1 μg/mL Anti-IFNAR1 (anifrolumab biosimilar) mAb (BME100117) on Expi293 cells transfected with Human IFNAR1 protein (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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