| Common Name | RO4858696-000,teprotumumab-trbw |
|---|---|
| Synonyms | CD221, IGFIR, IGFR, JTK13 |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions. |
| Host Species | Homo sapiens |
| IgG type | IgG1(E239D, M241L) |
| Reactivity | Human |
| Target | |
| Uniprot ID | P08069 |
| Description | Anti-IGF-1R(teprotumumab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-IGF-1R(teprotumumab biosimilar) mAb
Price: 50μg $82.00 ; 100 μg $162.00
Product Data
Images
Figure 1. IGF-1R protein is highly expressed on the surface of Expi293 cell membrane. Flow cytometry analysis with 1μg/mL Anti-IGF-1R(teprotumumab biosimilar) mAb (BME100174) on Expi293 cells transfected with human IGF-1R (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram),and Isotype antibody on Expi293 transfected with irrelevant protein (Orange histogram).
Figure 2. Flow cytometry analysis of antigen binding of anti-human IGF-1R mAb(BME100174).
(A) BME100174 does not bind to Jurkat cells that do not express IGF-1R.
(B) A clear peak shift of BME100174 was seen compared to the control when incubated with IGF-1R-expressing Hela cells, indicating strong binding of BME100174 to IGF-1R. Antibodies were incubated at 5 μg/mL.
Figure 3. Flow cytometry analysis of antigen binding of anti-human IGF-1R mAb(BME100174).
(A) BME100174 does not bind to Jurkat cells that do not express IGF-1R.
(B) A clear peak shift of BME100174 was seen compared to the control when incubated with IGF-1R-expressing MCF-7 cells, indicating strong binding of BME100174 to IGF-1R. Antibodies were incubated at 5 μg/mL.
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