| Clone ID | DMC422 |
|---|---|
| Target | |
| Synonyms | IBP-7; TAF; IGFBP-rP1; MAC25 protein |
| Host Species | Rabbit |
| Description | Anti-IGFBP7 antibody(DMC422); IgG1 Chimeric mAb |
| Delivery | In Stock |
| Uniprot ID | Q16270 |
| IgG type | Rabbit/Human Fc chimeric IgG1 |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt |
| Recommended Dilutions | Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity; and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity; and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene; and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-IGFBP7 antibody(DMC422); IgG1 Chimeric mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. Flow cytometry analysis with Anti-IGFBP7 (DMC422) on Expi293 cells transfected with human IGFBP7 (Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
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