| Clone ID | DM126 |
|---|---|
| Target | |
| Synonyms | CD217;CDw217;IL-17RA;IL17R;CANDF5;hIL-17R |
| Host Species | Rabbit |
| Description | Anti-IL17RA antibody(DM126); Rabbit mAb |
| Delivery | In Stock |
| Uniprot ID | Q96F46 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors; this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Usage | Research use only；All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
| Conjugate | Unconjugated |
Anti-IL17RA antibody(DM126); Rabbit mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. ELISA plate pre-coated by 1 μg/ml (100 μl/well) Human IL-17RA protein, His tagged protein (PME100468) can bind Rabbit anti-IL-17RA monoclonal antibody (clone: DM126) in a linear range of 0. 3-15 ng/ml.
Figure 2. Flow cytometry analysis with Anti-IL-17RA (DM126) on Expi293 cells transfected with human IL17RA(Blue histogram) or Expi293 transfected with irrelevant protein (Red histogram).
Related Products
Biosimilar reference antibodies
SKU: BME100038B Target: IL17RA
Application: ELISA; Flow Cyt
Price: 50μg $99.00 ; 100 μg $199.00
Biosimilar reference antibodies
SKU: BME100038P Target: IL17RA
Application: Flow Cyt
Price: 100 test $192.00
Biosimilar reference antibodies
SKU: BME100038 Target: IL17RA
Application: ELISA; Flow Cyt
Price: 50μg $82.00 ; 100 μg $162.00
Monoclonal antibodies
SKU: DME100125P Target: IL17RA
Application: Flow Cyt
Price: 100 test $550.00
ECD Proteins
SKU: PME100468 Target: IL17RA
Price: 10μg $82.00; 50μg $320.00 ; 100 μg $480.00