| Clone ID | DM116 |
|---|---|
| Target | |
| Synonyms | TNFRSF4; OX40; CD134; OX40L receptor; ACT35; TXGP1L |
| Host Species | Rabbit |
| Description | Anti-OX40 antibody(DM116); Rabbit mAb |
| Delivery | In Stock |
| Uniprot ID | P43489 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1:BCL2-XL; and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4 T cell response; as well as in T cell-dependent B cell proliferation and differentiation. |
| Usage | Research use only；All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
| Conjugate | Unconjugated |
Anti-OX40 antibody(DM116); Rabbit mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human OX40 protein, hFc-His tagged protein (PME100022) can bind Rabbit anti-OX40 monoclonal antibody (clone: DM116) in a linear range of 6-70 ng/ml.
Figure 2. Flow cytometry analysis with Anti-OX40 (DM116) on Expi293 cells transfected with human OX40 (Blue histogram) or Expi293 transfected with irrelevant protein(Red histogram).
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