| Clone ID | DM87 |
|---|---|
| Target | |
| Synonyms | PSCA;UNQ206;PRO232 |
| Host Species | Rabbit |
| Description | Anti-PSCA antibody(DM87); Rabbit mAb |
| Delivery | In Stock |
| Uniprot ID | O43653 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA; Flow Cyt; IHC |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100; IHC 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder; placenta; colon; kidney; and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-PSCA antibody(DM87), Rabbit mAb
Price: 10μg $99.00 ; 100 μg $446.00 ; 500 μg $1340.00
Product Data
Images
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human PSCA protein, hFc tagged protein PME100084 can bind Rabbit anti-PSCA monoclonal antibody (clone: DM87) in a linear range of 1-100 ng/ml.
Figure 2. Expi 293 cell line transfected with irrelevant protein (A) and human PSCA (B) were surface stained with Rabbit anti-PSCA monoclonal antibody 1μg/ml (clone: DM87) followed by Alexa 488-conjugated anti-rabbit IgG secondary antibody.
Figure 3. DME100087 at 10µg/ml staining PSCA in A431 xenografts in nude mice by IHC (SKU# DME100087)
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