| Common Name | IMMU-132, hRS7-SN-38, hRS7-SN-38-ADC, hRS7-[CL-SN-38], hrS7-SN-38 |
|---|---|
| Synonyms | TACSTD2;GA733-1;M1S1;TROP2 |
| Applications | ELISA; Flow Cyt |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Host Species | Humanized |
| IgG type | IgG1 |
| Reactivity | Human |
| Target | |
| Uniprot ID | P09758 |
| Description | Anti-Trop2 (sacituzumab biosimilar) mAb |
| Delivery | In Stock |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals. |
| Usage | Research use only |
| Conjugate | Unconjugated |
Anti-Trop2 (sacituzumab biosimilar) mAb
Price: 50μg $82.00 ; 100 μg $162.00
Product Data
Images
Figure 1. ELISA plate pre-coated by 2 μg/ml (100 μl/well) Human Trop2, mFc-His tagged protein PME100501 can bind Anti-Trop2 Neutralizing antibody in a linear range of 0.13-16.0 ng/ml.
Figure 2. Flow cytometry analysis of antigen binding of anti-human Trop2 mAb(BME100023).
(A) BME100023 does not bind to 293T cells that do not express Trop2.
(B) A clear peak shift of BME100023 was seen compared to the control when incubated with Trop2-expressing A431 cells, indicating strong binding of BME100023 to Trop2. Antibodies were incubated at 2 μg/mL.
Figure 3. HEK293 cell line transfected with irrelevant protein (B) and human Trop2 protein (A) were surface stained with anti-Trop2 neutralizing antibody 1μg/ml (sacituzumab) followed by Alexa 488-conjugated anti-human IgG secondary antibody.
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