| Clone ID | DM143 |
|---|---|
| Target | |
| Synonyms | BAFFR;TNFRSF13C;BAFF-R;BROMIX;CD268;CVID4;prolixin |
| Host Species | Rabbit |
| Description | Biotinylated Anti-BAFF-R antibody(DM143); Rabbit mAb |
| Delivery | 2-3 weeks |
| Uniprot ID | Q96RJ3 |
| IgG type | Rabbit IgG |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | ELISA; Flow Cyt; IHC |
| Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100; IHC 1:100 |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also; some SLE patients have increased levels of BAFF in serum. Therefore; it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. |
| Usage | Research use only；All DIMA recombinant antibodies are genuinely generated by DIMA Biotech. They are all under patent application. Any protein sequencing or reverse engineering attempt is prohibited. We are actively scrutinizing all patent application to ensure no IP infringement. |
| Conjugate | Biotinylated |
Biotinylated Anti-BAFF-R antibody(DM143); Rabbit mAb
Price: 10μg $139.00 ; 100 μg $670.00 ; 500 μg $1999.00
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