| Clone ID | DM4 |
|---|---|
| Target | |
| Synonyms | TNFRSF17 |
| Host Species | Rabbit |
| Description | Biotinylated Anti-BCMA bispecific antibody(DM4) |
| Delivery | 2-3 weeks |
| Uniprot ID | Q02223 |
| IgG type | Rabbit scfv |
| Clonality | Monoclonal |
| Reactivity | Human |
| Applications | Flow Cyt; MM Tumor cell killing |
| Recommended Dilutions | Flow Cyt 1:100; MMTumor cell killing |
| Purification | Purified from cell culture supernatant by affinity chromatography |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | BiTE bispecific antibody is an Engineered fusion protein constructed from two single-chain variable fragments (scFvs) of different monoclonal antibodies. One of the scFvs will be constructed from an anti-CD3 monoclonal antibody; and the other scFv fragment which linked by a linker region will be made from an anti-Tumor cell specific monoclonal antibody.The B-cell maturation protein (BCMA or BCM) is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes; and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily; member 13b (TNFSF13B:TALL-1:BAFF); and to lead to NF-kappaB and MAPK8:JNK activation. This receptor also binds to various TRAF family members; and thus may transduce signals for cell survival and proliferation. [provided by RefSeq; Jul 2008] |
| Usage | Research use only |
| Conjugate | Biotinylated |
Biotinylated Anti-BCMA bispecific antibody(DM4)
Price: 10μg $139.00 ; 100 μg $670.00 ; 500 μg $1999.00
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