Clone ID | DMC721 |
---|---|
Target | |
Synonyms | CD221; IGFIR; IGFR; JTK13 |
Host Species | Rabbit |
Description | Anti-IGF-1R antibody(DMC721); IgG1 Chimeric mAb |
Delivery | 2-3 weeks |
Uniprot ID | P08069 |
IgG type | Rabbit/Human Fc chimeric IgG1 |
Clonality | Monoclonal |
Reactivity | Human |
Applications | Flow Cyt |
Recommended Dilutions | Flow Cyt 1/100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014] |
Usage | Research use only |
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Biotinylated Anti-IGF-1R antibody(DMC721), IgG1 Chimeric mAb
Price: 10μg $139.00 ; 100 μg $670.00 ; 500 μg $1999.00