Clone ID | DM83 |
---|---|
Target | |
Synonyms | HAVCR2; TIM3; TIMD3; FLJ14428; KIM3 |
Host Species | Rabbit |
Description | Biotinylated Anti-TIM3 antibody(DM83); Rabbit mAb |
Delivery | 2-3 weeks |
Uniprot ID | Q8TDQ0 |
IgG type | Rabbit IgG |
Clonality | Monoclonal |
Reactivity | Human |
Applications | ELISA; Flow Cyt |
Recommended Dilutions | ELISA 1:5000-10000; Flow Cyt 1:100 |
Purification | Purified from cell culture supernatant by affinity chromatography |
Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
Background | The protein encoded by this gene belongs to the immunoglobulin superfamily; and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions; whereas; Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation; and inhibits Th1-mediated auto- and alloimmune responses; and promotes immunological tolerance. |
Usage | Research use only |
Conjugate | Biotinylated |
Biotinylated Anti-TIM3 antibody(DM83); Rabbit mAb
Price: 10μg $139.00 ; 100 μg $670.00 ; 500 μg $1999.00
Product Data
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